Therapy and clinical trials.
نویسنده
چکیده
The year 2011 has thus far been dominated by the vigorous pursuit of interventions for patients with low levels of high-density lipoprotein cholesterol (HDL-C) and proatherogenic lipid profiles. The major setback of the early stoppage of the Atherothrombosis Intervention in Metabolic Syndrome with Low HDL Cholesterol/ High Triglyceride and Impact on Global Health Outcomes (AIM-HIGH) trial by the National Heart, Lung, and Blood Institute (NHLBI) [1] was seemingly offset by the demonstrated safety of the cholesteryl ester transfer protein (CETP) inhibitor dalcetrapib in the dal-VESSEL trial [2].
منابع مشابه
Clinical Applicability of Stem Cell Therapy in Dental Diseases: A Systematic Review of Available Clinical Trials
Background: Developing cell-based therapeutic methods for the differentiation of various stem cells to the dental tissues could be a revolutionary step towards the use of cell therapy for dental disease. In the present study, we aimed to systematically review the literature to establish the efficiency of stem cells in treatment of various dental diseases. Methods: A literature search was perfo...
متن کاملHematopoietic stem cell transplant therapy, clinical trials, complications, and quality of life for patients with Sickle cell anemia: Clinical potential and future perspectives
Background: Sickle cell anemia (SCA) is an inherited monogenic disorder. The clinical symptoms of SCA are protean, including vaso-occlusion, hemolysis, early stroke, leg ulcers, multi-organ failure, and increased risk of premature death. Hematopoietic stem cell transplantation is the only treatment identified to reduce SCA-related organ damage. Unfortunately, graft rejection is a significant im...
متن کاملCell Therapy in Cardiovascular Disease
Recently, cell therapy has sparked a revolution in ischemic heart disease that will in the future help clinicians to cure patients. Earlier investigations in animal models and clinical trials have suggested that positive paracrine effects such as neoangiogenesis and anti-apoptotic can improve myocardial function. In this regard the Royan cell therapy center designed a few trials in collaborat...
متن کاملP-46: The Effect of Oral Antioxidants on Male Infertility
Background: The use of antioxidants in treatment of infertile men has been suggested, although the evidence base for this practice is unclear. A systematic review of randomized studies was conducted to evaluate the effects of oral antioxidants (vitamins C and E, zinc, selenium, folate, carnitine and carotenoids) on sperm quality and pregnancy rate in infertile men. Materials and Methods: MEDLIN...
متن کاملThe Effectiveness of Exercise Therapy on Improving Pain and Functional Disability in Patients with Non-Specific Chronic Low Back Pain: A Systematic Review of English Clinical Trials
Aims and background: Chronic low back pain (LBP) is one of the most common and costly musculoskeletal disorders in societies that have been suggested for many therapies. Exercise therapy is one of the most widely used methods in control and treatment of chronic low back pain. The purpose of the present study is to systematically review English-language studies that have investigated the effect...
متن کاملPotential use of Dental Pulp Stem Cell in Laboratory Studies and Clinical Trials
Stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type I diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations and cancer. In addition to their potential use to treat systemic diseases, stem cell-based therapy also provides a powerful tool to treat oral and dental diseases such as cra...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Current opinion in lipidology
دوره 26 1 شماره
صفحات -
تاریخ انتشار 2008